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A Method of Lyophilizing Vaccines Containing Aluminum Salts into a Dry Powder Without Causing Particle Aggregation or Decreasing the Immunogenicity Following Reconstitution

Many currently licensed and commercially available human vaccines contain aluminum salts as vaccine adjuvants. A major limitation with these vaccines is that they must not be exposed to freezing temperatures during transport or storage such that the liquid vaccine freezes, because freezing causes ir...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Li, Xinran, Thakkar, Sachin G., Ruwona, Tinashe B., Williams, Robert O., Cui, Zhengrong
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385422/
https://ncbi.nlm.nih.gov/pubmed/25735896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.02.035
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