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The effect of radiation exposure on multidrug resistance: in vitro and in vivo studies using non-small lung cancer cells

BACKGROUND: Technetium-99m methoxyisobutylisonitrile (Tc MIBI) is a substrate with the same uptake kinetics as doxorubicin. Multidrug resistance (MDR) is a mechanism that impedes chemotherapy of non-small cell lung cancer (NSCLC). We examined the effect of radiation exposure on MDR in NSCLC and the...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Kanno, Shohei, Utsunomiya, Keita, Kono, Yumiko, Tanigawa, Noboru, Sawada, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385263/
https://ncbi.nlm.nih.gov/pubmed/25853017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0091-5
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