Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism

Venous thromboembolism (VTE), the third leading cause of cardiovascular mortality, is a complex thrombotic disorder with environmental and genetic determinants. Although several genetic variants have been found associated with VTE, they explain a minor proportion of VTE risk in cases. We undertook a...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Germain, Marine, Chasman, Daniel I., de Haan, Hugoline, Tang, Weihong, Lindström, Sara, Weng, Lu-Chen, de Andrade, Mariza, de Visser, Marieke C.H., Wiggins, Kerri L., Suchon, Pierre, Saut, Noémie, Smadja, David M., Le Gal, Grégoire, van Hylckama Vlieg, Astrid, Di Narzo, Antonio, Hao, Ke, Nelson, Christopher P., Rocanin-Arjo, Ares, Folkersen, Lasse, Monajemi, Ramin, Rose, Lynda M., Brody, Jennifer A., Slagboom, Eline, Aïssi, Dylan, Gagnon, France, Deleuze, Jean-Francois, Deloukas, Panos, Tzourio, Christophe, Dartigues, Jean-Francois, Berr, Claudine, Taylor, Kent D., Civelek, Mete, Eriksson, Per, Psaty, Bruce M., Houwing-Duitermaat, Jeanine, Goodall, Alison H., Cambien, François, Kraft, Peter, Amouyel, Philippe, Samani, Nilesh J., Basu, Saonli, Ridker, Paul M., Rosendaal, Frits R., Kabrhel, Christopher, Folsom, Aaron R., Heit, John, Reitsma, Pieter H., Trégouët, David-Alexandre, Smith, Nicholas L., Morange, Pierre-Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385184/
https://ncbi.nlm.nih.gov/pubmed/25772935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.01.019
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