Comparison of 4′-[methyl-(11)C]thiothymidine ((11)C-4DST) and 3′-deoxy-3′-[(18)F]fluorothymidine ((18)F-FLT) PET/CT in human brain glioma imaging

BACKGROUND: 3′-deoxy-3′-[(18)F]fluorothymidine ((18)F-FLT) has been used to evaluate tumor malignancy and cell proliferation in human brain gliomas. However, (18)F-FLT has several limitations in clinical use. Recently, (11)C-labeled thymidine analogue, 4′-[methyl-(11)C]thiothymidine ((11)C-4DST), be...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Toyota, Yasunori, Miyake, Keisuke, Kawai, Nobuyuki, Hatakeyama, Tetsuhiro, Yamamoto, Yuka, Toyohara, Jun, Nishiyama, Yoshihiro, Tamiya, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385144/
https://ncbi.nlm.nih.gov/pubmed/25853013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0085-3
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