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Biologic Effects of Anti-Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Antibody Formation in Patients Treated with GM-CSF (Sargramostim) as Adjuvant Therapy of Melanoma

OBJECTIVES: We investigated the development of binding and neutralizing antibodies to GM-CSF in patients receiving prolonged therapy with GM-CSF as adjuvant therapy of melanoma and the impact of these antibodies on biologic effects. METHODS: Fifty-three patients with high-risk melanoma which had bee...

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Bibliografske podrobnosti
izdano v:Am J Clin Oncol
Main Authors: Spitler, Lynn E., Cao, Huynh, Piironen, Timo, Whiteside, Theresa L., Weber, Robert W., Cruickshank, Scott
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385005/
https://ncbi.nlm.nih.gov/pubmed/25286079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COC.0000000000000124
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