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Intracellular Redox State Revealed by In Vivo (31)P MRS Measurement of NAD(+) and NADH Contents in Brains

PURPOSE: Nicotinamide adenine dinucleotide (NAD), in oxidized (NAD(+)) or reduced (NADH) form, plays key roles in cellular metabolism. Intracellular NAD(+)/NADH ratio represents the cellular redox state; however, it is difficult to measure in vivo. We report here a novel in vivo (31)P MRS method for...

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Bibliographic Details
Published in:Magn Reson Med
Main Authors: Lu, Ming, Zhu, Xiao-Hong, Zhang, Yi, Chen, Wei
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384818/
https://ncbi.nlm.nih.gov/pubmed/23843330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24859
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