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Noninvasive Molecular Imaging of Apoptosis in a Mouse Model of Anthracycline-Induced Cardiotoxicity
BACKGROUND: Anthracycline-induced cardiotoxicity and myocardial dysfunction may be associated with apoptosis. Caspase 3 catalyzes a terminal step in apoptosis, and its expression may serve as a marker of cardiomyocyte apoptosis. We synthesized 18F-CP18, a caspase-3 substrate and evaluated cardiac 18...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Circ Cardiovasc Imaging |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384653/ https://ncbi.nlm.nih.gov/pubmed/25657296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.114.001952 |
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