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SNP CHARACTERISTICS PREDICT REPLICATION SUCCESS IN ASSOCIATION STUDIES

Successful independent replication is the most direct approach for distinguishing real genotype-disease associations from false discoveries in Genome Wide Association Studies (GWAS). Selecting SNPs for replication has been primarily based on p-values from the discovery stage, although additional cha...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Gorlov, Ivan P., Moore, Jason H., Peng, Bo, Jin, Jennifer L., Gorlova, Olga Y., Amos, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384517/
https://ncbi.nlm.nih.gov/pubmed/25273843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-014-1493-6
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