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Interferons and viruses: an evolutionary arms race of molecular interactions

Over half a century has passed since interferons (IFNs) were discovered and shown to inhibit virus infection in cultured cells. Since then, researchers have steadily brought to light the molecular details of IFN signaling, catalogued their pleiotropic effects on cells, and harnessed their therapeuti...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Hoffmann, Hans-Heinrich, Schneider, William M., Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384471/
https://ncbi.nlm.nih.gov/pubmed/25704559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.01.004
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