Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans

The UDP-glucuronosylatransferase 1A1 (UGT1A1) gene is involved in the metabolism of estrogen and detoxification of potential carcinogens. The number of TA repeats in the promoter region of UGT1A1 has been linked to breast cancer risk, but results varied by race. We performed a comprehensive assessme...

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Udgivet i:Breast Cancer Res Treat
Main Authors: Huo, Dezheng, Kim, Hee-Jin, Adebamowo, Clement A., Ogundiran, Temidayo O., Akang, Effiong E., Campbell, Oladapo, Adenipekun, Adeniyi, Niu, Qun, Sveen, Lise, Fackenthal, James D., Fackenthal, Donna Lee, Das, Soma, Cox, Nancy, Di Rienzo, Anna, Olopade, Olufunmilayo I.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384416/
https://ncbi.nlm.nih.gov/pubmed/17909964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-007-9720-7
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