The time-course and RNA interference of TNF-α, IL-6, and IL-1β expression on neuropathic pain induced by L5 spinal nerve transection in rats

BACKGROUND: The objective of this study was to investigate the time-course of the expression of TNF-α, IL-6, and IL-1β after L5 spinal nerve transection (SNT), and to determine the effect of small interfering RNA (siRNA) targeting these cytokines on neuropathic pain. METHODS: Rats received control s...

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Detalhes bibliográficos
Publicado no:Korean J Anesthesiol
Main Authors: Choi, Byung Moon, Lee, Soo Han, An, Sang Mee, Park, Do Yang, Lee, Gwan Woo, Noh, Gyu-Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Anesthesiologists 2015
Assuntos:
Experimental Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384404/
https://ncbi.nlm.nih.gov/pubmed/25844135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kjae.2015.68.2.159
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