Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry

INTRODUCTION: The objective of this study was to directly compare the safety of tocilizumab (TCZ) and TNF inhibitors (TNFIs) in rheumatoid arthritis (RA) patients in clinical practice. METHODS: This prospective cohort study included RA patients starting TCZ [TCZ group, n = 302, 224.68 patient-years...

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Publicado en:Arthritis Res Ther
Autores principales: Sakai, Ryoko, Cho, Soo-Kyung, Nanki, Toshihiro, Watanabe, Kaori, Yamazaki, Hayato, Tanaka, Michi, Koike, Ryuji, Tanaka, Yoshiya, Saito, Kazuyoshi, Hirata, Shintaro, Amano, Koichi, Nagasawa, Hayato, Sumida, Takayuki, Hayashi, Taichi, Sugihara, Takahiko, Dobashi, Hiroaki, Yasuda, Shinsuke, Sawada, Tetsuji, Ezawa, Kazuhiko, Ueda, Atsuhisa, Fujii, Takao, Migita, Kiyoshi, Miyasaka, Nobuyuki, Harigai, Masayoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384380/
https://ncbi.nlm.nih.gov/pubmed/25880658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0583-8
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