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Evaluating the efficacy, safety and evolution of renal function with early initiation of everolimus-facilitated tacrolimus reduction in de novo liver transplant recipients: Study protocol for a randomized controlled trial

BACKGROUND: Introduction of calcineurin inhibitors had led to improved survival rates in liver transplant recipients. However, long-term use of calcineurin inhibitors is associated with a higher risk of chronic renal failure, neurotoxicity, de novo malignancies, recurrence of hepatitis C viral (HCV)...

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發表在:Trials
Main Authors: Nashan, Bjorn, Schemmer, Peter, Braun, Felix, Dworak, Markus, Wimmer, Peter, Schlitt, Hans
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384314/
https://ncbi.nlm.nih.gov/pubmed/25873064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0626-0
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