Rapid and accurate estimates of statistical significance for sequence data base searches.
A central question in sequence comparison is the statistical significance of an observed similarity. For local alignment containing gaps to optimize sequence similarity this problem has so far not been solved mathematically. Using as a basis the Chen-Stein theory of Poisson approximation, we present...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4625 |
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