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Bayesian Nonparametric Estimation of Targeted Agent Effects on Biomarker Change to Predict Clinical Outcome

The effect of a targeted agent on a cancer patient's clinical outcome putatively is mediated through the agent's effect on one or more early biological events. This is motivated by pre-clinical experiments with cells or animals that identify such events, represented by binary or quantitati...

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Vydáno v:Biometrics
Hlavní autoři: Graziani, Rebecca, Guindani, Michele, Thall, Peter F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383707/
https://ncbi.nlm.nih.gov/pubmed/25319212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12250
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