Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear. In a recent large rat genome-wide expression profiling and linkage analysis we found co-regulation of complement C3 immediately downstream of butyrylcholi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Aeinehband, Shahin, Lindblom, Rickard P. F., Al Nimer, Faiez, Vijayaraghavan, Swetha, Sandholm, Kerstin, Khademi, Mohsen, Olsson, Tomas, Nilsson, Bo, Ekdahl, Kristina Nilsson, Darreh-Shori, Taher, Piehl, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383591/
https://ncbi.nlm.nih.gov/pubmed/25835709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122048
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