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Transient Receptor Potential Melastatin-4 Is Involved in Hypoxia-Reoxygenation Injury in the Cardiomyocytes

Ischemic heart disease still remains the most common cause of cardiac death. During ischemia-reperfusion (I/R), reactive oxygen species (ROS) are produced in excess in cardiac tissue, where they induce cell death. Our previous study showed that 9-phenanthrol (9-Phe), a specific inhibitor of the TRPM...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Piao, Hulin, Takahashi, Ken, Yamaguchi, Yohei, Wang, Chen, Liu, Kexiang, Naruse, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383534/
https://ncbi.nlm.nih.gov/pubmed/25836769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121703
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