Soluble α-Klotho Serum Levels in Chronic Kidney Disease

Transmembrane α-Klotho (TM-Klotho), expressed in renal tubules, is a cofactor for FGF23-receptor. Circulating soluble-α-Klotho (s-Klotho) results from TM-Klotho shedding and acts on Phosphate (P) and Calcium (Ca) tubular transport. Decreased TM-Klotho, described in experimental chronic kidney diseas...

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Dades bibliogràfiques
Publicat a:Int J Endocrinol
Autors principals: Rotondi, Silverio, Pasquali, Marzia, Tartaglione, Lida, Muci, Maria Luisa, Mandanici, Giusy, Leonangeli, Cristiana, Sales, Silvia, Farcomeni, Alessio, Mazzaferro, Sandro
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383388/
https://ncbi.nlm.nih.gov/pubmed/25873958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/872193
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