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Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells

Dopaminergic (DA) neurons in the substantia nigra pars compacta (also known as A9 DA neurons) are the specific cell type that is lost in Parkinson’s disease (PD). There is great interest in deriving A9 DA neurons from human pluripotent stem cells (hPSCs) for regenerative cell replacement therapy for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Zhang, Pengbo, Xia, Ninuo, Reijo Pera, Renee A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383321/
https://ncbi.nlm.nih.gov/pubmed/25285746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51737
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