Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

Neurofibromatosis 1 is a hereditary syndrome characterized by the development of numerous benign neurofibromas, a small subset of which progress to malignant peripheral nerve sheath tumors (MPNSTs). To better understand the genetic basis for MPNSTs, we performed genome-wide or targeted sequencing on...

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Udgivet i:Nat Genet
Main Authors: Zhang, Ming, Wang, Yuxuan, Jones, Sian, Sausen, Mark, McMahon, Kevin, Sharma, Rajni, Wang, Qing, Belzberg, Allan J, Chaichana, Kaisorn, Gallia, Gary L, Gokaslan, Ziya L, Riggins, Greg J, Wolinksy, Jean-Paul, Wood, Laura D, Montgomery, Elizabeth A, Hruban, Ralph H, Kinzler, Kenneth W, Papadopoulos, Nickolas, Vogelstein, Bert, Bettegowda, Chetan
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383254/
https://ncbi.nlm.nih.gov/pubmed/25305755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3116
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