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Enhanced stability and polyadenylation of select mRNAs support rapid thermogenesis in the brown fat of a hibernator

During hibernation, animals cycle between torpor and arousal. These cycles involve dramatic but poorly understood mechanisms of dynamic physiological regulation at the level of gene expression. Each cycle, Brown Adipose Tissue (BAT) drives periodic arousal from torpor by generating essential heat. W...

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Publicat a:eLife
Autors principals: Grabek, Katharine R, Diniz Behn, Cecilia, Barsh, Gregory S, Hesselberth, Jay R, Martin, Sandra L
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383249/
https://ncbi.nlm.nih.gov/pubmed/25626169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04517
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