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Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder

BACKGROUND: Bipolar affective disorder (BP) is a common, highly heritable psychiatric disorder characterized by periods of depression and mania. Using dense SNP genotype data, we characterized CNVs in 388 members of an Old Order Amish Pedigree with bipolar disorder. We identified CNV regions arising...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Kember, Rachel L, Georgi, Benjamin, Bailey-Wilson, Joan E, Stambolian, Dwight, Paul, Steven M, Bućan, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382929/
https://ncbi.nlm.nih.gov/pubmed/25887117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0184-1
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