BRCA1 Is a Histone-H2A-Specific Ubiquitin Ligase

The RING domain proteins BRCA1 and BARD1 comprise a heterodimeric ubiquitin (E3) ligase that is required for the accumulation of ubiquitin conjugates at sites of DNA damage and for silencing at DNA satellite repeat regions. Despite its links to chromatin, the substrate and underlying function of the...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Kalb, Reinhard, Mallery, Donna L., Larkin, Conor, Huang, Jeffrey T.J., Hiom, Kevin
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2014
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382519/
https://ncbi.nlm.nih.gov/pubmed/25131202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.025
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars