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Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction.

The cell surface of mammalian cells is capable of reductively cleaving disulfide bonds of exogenous membrane-bound macromolecules (for instance, the interchain disulfide of diphtheria toxin), and inhibiting this process with membrane-impermeant sulfhydryl reagents prevents diphtheria toxin cytotoxic...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ryser, H J, Levy, E M, Mandel, R, DiSciullo, G J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43825/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4559
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