Inverse Agonistic Action of 3-Iodothyronamine at the Human Trace Amine-Associated Receptor 5

Objective Application of 3-iodothyronamine (3-T(1)AM) results in decreased body temperature and body weight in rodents. The trace amine-associated receptor (TAAR) 1, a family A G protein-coupled receptor, is a target of 3-T(1)AM. However, 3-T(1)AM effects still persist in mTaar1 knockout mice, which...

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Publicado en:PLoS One
Main Authors: Dinter, Juliane, Mühlhaus, Jessica, Wienchol, Carolin Leonie, Yi, Chun-Xia, Nürnberg, Daniela, Morin, Silke, Grüters, Annette, Köhrle, Josef, Schöneberg, Torsten, Tschöp, Matthias, Krude, Heiko, Kleinau, Gunnar, Biebermann, Heike
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382497/
https://ncbi.nlm.nih.gov/pubmed/25706283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117774
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