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Conditional genetic deletion of PTEN after a spinal cord injury enhances regenerative growth of CST axons and motor function recovery in mice

Previous studies indicate that conditional genetic deletion of phosphatase and tensin homolog (PTEN) in neonatal mice enhances the ability of axons to regenerate following spinal cord injury (SCI) in adults. Here, we assessed whether deleting PTEN in adult neurons post-SCI is also effective, and whe...

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Détails bibliographiques
Publié dans:Exp Neurol
Auteurs principaux: Danilov, Camelia A., Steward, Oswald
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382431/
https://ncbi.nlm.nih.gov/pubmed/25704959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.02.012
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