Four-Dimensional Characterization of Thrombosis in a Live-Cell, Shear-Flow Assay: Development and Application to Xenotransplantation

BACKGROUND: Porcine xenografts are a promising source of scarce transplantable organs, but stimulate intense thrombosis of human blood despite targeted genetic and pharmacologic interventions. Current experimental models do not enable study of the blood/endothelial interface to investigate adhesive...

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Udgivet i:PLoS One
Main Authors: Harris, Donald G., Benipal, Prabhjot K., Cheng, Xiangfei, Burdorf, Lars, Azimzadeh, Agnes M., Pierson, Richard N.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382176/
https://ncbi.nlm.nih.gov/pubmed/25830912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123015
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