Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G Protein-Coupled Prokineticin Receptor-1

Prokineticins are angiogenic hormones that activate two G protein-coupled receptors: PKR1 and PKR2. PKR1 has emerged as a critical mediator of cardiovascular homeostasis and cardioprotection. Identification of non-peptide PKR1 agonists that contribute to myocardial repair and collateral vessel growt...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Gasser, Adeline, Brogi, Simone, Urayama, Kyoji, Nishi, Toshishide, Kurose, Hitoshi, Tafi, Andrea, Ribeiro, Nigel, Désaubry, Laurent, Nebigil, Canan G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382091/
https://ncbi.nlm.nih.gov/pubmed/25831128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121027
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