Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but generally absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in human cancers and...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Katz, Yarden, Li, Feifei, Lambert, Nicole J, Sokol, Ethan S, Tam, Wai-Leong, Cheng, Albert W, Airoldi, Edoardo M, Lengner, Christopher J, Gupta, Piyush B, Yu, Zhengquan, Jaenisch, Rudolf, Burge, Christopher B
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Genomics and Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381951/
https://ncbi.nlm.nih.gov/pubmed/25380226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03915
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