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Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes

Adjudin is a derivative of 1H-indazole-3-carboxylic acid that was shown to have potent anti-spermatogenic activity in rats, rabbits, and dogs. It exerts its effects most notably locally in the apical compartment of the seminiferous epithelium, behind the blood–testis barrier, by disrupting adhesion...

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Publicado en:Reproduction
Autores principales: Mok, Ka-Wai, Mruk, Dolores D, Lie, Pearl P Y, Lui, Wing-Yee, Cheng, C Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381908/
https://ncbi.nlm.nih.gov/pubmed/21307270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-10-0464
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