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Structure and transport mechanism of the sodium/proton antiporter MjNhaP1

Sodium/proton antiporters are essential for sodium and pH homeostasis and play a major role in human health and disease. We determined the structures of the archaeal sodium/proton antiporter MjNhaP1 in two complementary states. The inward-open state was obtained by x-ray crystallography in the prese...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Paulino, Cristina, Wöhlert, David, Kapotova, Ekaterina, Yildiz, Özkan, Kühlbrandt, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381896/
https://ncbi.nlm.nih.gov/pubmed/25426803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03583
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