Development of sample clean up methods for the analysis of Mycobacterium tuberculosis methyl mycocerosate biomarkers in sputum extracts by gas chromatography–mass spectrometry

A proof of principle gas chromatography–mass spectrometry method is presented, in combination with clean up assays, aiming to improve the analysis of methyl mycocerosate tuberculosis biomarkers from sputum. Methyl mycocerosates are generated from the transesterification of phthiocerol dimycocerosate...

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Detalhes bibliográficos
Publicado no:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Nicoara, Simona C., Turner, Nicholas W., Minnikin, David E., Lee, Oona Y.-C., O'Sullivan, Denise M., McNerney, Ruth, Mutetwa, Reggie, Corbett, Liz E., Morgan, Geraint H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381843/
https://ncbi.nlm.nih.gov/pubmed/25728371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.02.010
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