Krüppel-associated boxes are potent transcriptional repression domains.

The Krüppel-associated box (KRAB) is a highly conserved, 75-aa region containing two predicted amphipathic alpha-helices. The KRAB domain is present in the amino-terminal regions of more than one-third of all Krüppel-class Cys2His2 zinc finger proteins and is conserved from yeast to man; however, it...

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Main Authors: Margolin, J F, Friedman, J R, Meyer, W K, Vissing, H, Thiesen, H J, Rauscher, F J
格式: Artigo
語言:Inglês
出版: 1994
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC43815/
https://ncbi.nlm.nih.gov/pubmed/8183939
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