Krüppel-associated boxes are potent transcriptional repression domains.
The Krüppel-associated box (KRAB) is a highly conserved, 75-aa region containing two predicted amphipathic alpha-helices. The KRAB domain is present in the amino-terminal regions of more than one-third of all Krüppel-class Cys2His2 zinc finger proteins and is conserved from yeast to man; however, it...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4509 |
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