Mir-24-3p downregulation contributes to VP16–DDP resistance in small-cell lung cancer by targeting ATG4A

Although the combination of etoposide (VP16) and cisplatin (DDP) is widely used as a first-line treatment for advanced-stage small-cell lung cancer (SCLC), chemoresistance limits its clinical use. Abnormalities of autophagy are associated with tumor chemoresistance. The present study found that miR-...

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Опубликовано в: :Oncotarget
Главные авторы: Pan, Banzhou, Chen, Yitian, Song, Haizhu, Xu, Yichen, Wang, Rui, Chen, Longbang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2014
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381597/
https://ncbi.nlm.nih.gov/pubmed/25426560
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