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The role of DNA methylation in directing the functional organization of the cancer epigenome

The holistic role of DNA methylation in the organization of the cancer epigenome is not well understood. Here we perform a comprehensive, high-resolution analysis of chromatin structure to compare the landscapes of HCT116 colon cancer cells and a DNA methylation-deficient derivative. The NOMe-seq ac...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Lay, Fides D., Liu, Yaping, Kelly, Theresa K., Witt, Heather, Farnham, Peggy J., Jones, Peter A., Berman, Benjamin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381519/
https://ncbi.nlm.nih.gov/pubmed/25747664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.183368.114
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