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Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment

BACKGROUND: Decreased expression of glucose transporter protein GLUT4, encoded by the solute carrier 2A4 (Slc2a4) gene, is involved in obesity-induced insulin resistance. Local tissue inflammation, by nuclear factor-κB (NFκB)-mediated pathway, has been related to Slc2a4 repression; a mechanism that...

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Detalhes bibliográficos
Publicado no:Diabetol Metab Syndr
Main Authors: Poletto, Ana Cláudia, David-Silva, Aline, Yamamoto, Aline Pedro de Melo, Machado, Ubiratan Fabres, Furuya, Daniela Tomie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381373/
https://ncbi.nlm.nih.gov/pubmed/25834641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0015-6
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