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Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines

Tumor repopulation after radiotherapy is a big obstacle for clinical cancer therapy. The molecular mechanisms of tumor cell repopulation after radiotherapy remain unclear. This study investigated the role of sonic hedgehog (SHH) and Wnt signaling pathways in tumor repopulation after radiotherapy in...

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發表在:Dis Model Mech
Main Authors: Ma, Jingjing, Cheng, Jin, Gong, Yanping, Tian, Ling, Huang, Qian
格式: Artigo
語言:Inglês
出版: The Company of Biologists Limited 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381337/
https://ncbi.nlm.nih.gov/pubmed/25713298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.018887
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