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Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines

Tumor repopulation after radiotherapy is a big obstacle for clinical cancer therapy. The molecular mechanisms of tumor cell repopulation after radiotherapy remain unclear. This study investigated the role of sonic hedgehog (SHH) and Wnt signaling pathways in tumor repopulation after radiotherapy in...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Ma, Jingjing, Cheng, Jin, Gong, Yanping, Tian, Ling, Huang, Qian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Limited 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381337/
https://ncbi.nlm.nih.gov/pubmed/25713298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.018887
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