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A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia

Neuropathic pain is characterized by mechanical allodynia induced by low-threshold myelinated Aβ-fiber activation. The original gate theory of pain proposes that inhibitory interneurons in the lamina II of the spinal dorsal horn (DH) act as “gate control” units for preventing the interaction between...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lu, Yan, Dong, Hailong, Gao, Yandong, Gong, Yuanyuan, Ren, Yingna, Gu, Nan, Zhou, Shudi, Xia, Nan, Sun, Yan-Yan, Ji, Ru-Rong, Xiong, Lize
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381282/
https://ncbi.nlm.nih.gov/pubmed/23979158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70026
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