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Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl(+) K562 and Jak2(V617F)(+) HEL Leukemia Cells

Signal transducers and activators of transcription (Stats) play central roles in the conversion of extracellular signals, e.g., cytokines, hormones and growth factors, into tissue and cell type specific gene expression patterns. In normal cells, their signaling potential is strictly limited in exten...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Weber, Axel, Borghouts, Corina, Brendel, Christian, Moriggl, Richard, Delis, Natalia, Brill, Boris, Vafaizadeh, Vida, Groner, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381271/
https://ncbi.nlm.nih.gov/pubmed/25809097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7010503
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