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Immunreconstitution and Infectious Complications After Rituximab Treatment in Children and Adolescents: What Do We Know and What Can We Learn from Adults?

Rituximab, an anti CD20 monoclonal antibody, is widely used in the treatment of B-cell malignancies in adults and increasingly in pediatric patients. By depleting B-cells, rituximab interferes with humoral immunity. This review provides a comprehensive overview of immune reconstitution and infectiou...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Worch, Jennifer, Makarova, Olga, Burkhardt, Birgit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381260/
https://ncbi.nlm.nih.gov/pubmed/25643241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7010305
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