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Normal Distribution of CD8+ T-Cell-Derived ELISPOT Counts within Replicates Justifies the Reliance on Parametric Statistics for Identifying Positive Responses

Accurate assessment of positive ELISPOT responses for low frequencies of antigen-specific T-cells is controversial. In particular, it is still unknown whether ELISPOT counts within replicate wells follow a theoretical distribution function, and thus whether high power parametric statistics can be us...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: Karulin, Alexey Y., Caspell, Richard, Dittrich, Marcus, Lehmann, Paul V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381212/
https://ncbi.nlm.nih.gov/pubmed/25738924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells4010096
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