Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment

The class II transactivator (CIITA) is essential for the expression of major histocompatibility complex class II (MHC-II) genes; however, the role of CIITA in gene regulation outside of MHC-II biology is not fully understood. To comprehensively map CIITA-bound loci, ChIP-seq was performed in the hum...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Scharer, Christopher D., Choi, Nancy M., Barwick, Benjamin G., Majumder, Parimal, Lohsen, Sarah, Boss, Jeremy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381081/
https://ncbi.nlm.nih.gov/pubmed/25753668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv182
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