Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex

The yeast KEOPS protein complex comprising Kae1, Bud32, Cgi121, Pcc1 and Gon7 is responsible for the essential tRNA threonylcarbamoyladenosine (t(6)A) modification. Deletion of genes coding for the KEOPS subunits also affects telomere elongation and transcriptional regulation. In the present work, t...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Zhang, Wenhua, Collinet, Bruno, Graille, Marc, Daugeron, Marie-Claire, Lazar, Noureddine, Libri, Domenico, Durand, Dominique, van Tilbeurgh, Herman
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381065/
https://ncbi.nlm.nih.gov/pubmed/25735745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv155
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