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Kinetochore–microtubule error correction is driven by differentially regulated interaction modes

For proper chromosome segregation, sister kinetochores must interact with microtubules from opposite spindle poles (bi-orientation). To establish bi-orientation, aberrant kinetochore–microtubule attachments are disrupted (error correction) by Aurora B kinase (Ipl1 in budding yeast). Paradoxically, d...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Kalantzaki, Maria, Kitamura, Etsushi, Zhang, Tongli, Mino, Akihisa, Novák, Béla, Tanaka, Tomoyuki U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380510/
https://ncbi.nlm.nih.gov/pubmed/25751138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3128
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