G-Protein-Coupled Estrogen Receptor Agonist Suppresses Airway Inflammation in a Mouse Model of Asthma through IL-10

Estrogen influences the disease severity and sexual dimorphism in asthma, which is caused by complex mechanisms. Besides classical nuclear estrogen receptors (ERαβ), G-protein-coupled estrogen receptor (GPER) was recently established as an estrogen receptor on the cell membrane. Although GPER is ass...

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Veröffentlicht in:PLoS One
Hauptverfasser: Itoga, Masamichi, Konno, Yasunori, Moritoki, Yuki, Saito, Yukiko, Ito, Wataru, Tamaki, Mami, Kobayashi, Yoshiki, Kayaba, Hiroyuki, Kikuchi, Yuta, Chihara, Junichi, Takeda, Masahide, Ueki, Shigeharu, Hirokawa, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380451/
https://ncbi.nlm.nih.gov/pubmed/25826377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123210
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