The Invadopodia Scaffold Protein Tks5 Is Required for the Growth of Human Breast Cancer Cells In Vitro and In Vivo

The ability of cancer cells to invade underlies metastatic progression. One mechanism by which cancer cells can become invasive is through the formation of structures called invadopodia, which are dynamic, actin-rich membrane protrusions that are sites of focal extracellular matrix degradation. Whil...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Blouw, Barbara, Patel, Manishha, Iizuka, Shinji, Abdullah, Christopher, You, Weon Kyoo, Huang, Xiayu, Li, Jian-Liang, Diaz, Begoña, Stallcup, William B., Courtneidge, Sara A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380437/
https://ncbi.nlm.nih.gov/pubmed/25826475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121003
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