Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells

Alterations in mucin expression and glycosylation are associated with cancer development. Underglycosylated mucin-1 (uMUC1) is overexpressed in most malignant adenocarcinomas of epithelial origin (for example, colon, breast and ovarian cancer). Its counterpart MUC1 is a large polymer rich in glycans...

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Опубликовано в: :Nat Commun
Главные авторы: Song, Xiaolei, Airan, Raag D., Arifin, Dian R., Bar-Shir, Amnon, Kadayakkara, Deepak K., Liu, Guanshu, Gilad, Assaf A., van Zijl, Peter C. M., McMahon, Michael T., Bulte, Jeff W. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380237/
https://ncbi.nlm.nih.gov/pubmed/25813863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7719
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