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Notch1-Dll4 signaling and mechanical force regulate leader cell formation during collective cell migration

At the onset of collective cell migration, a subset of cells within an initially homogenous population acquires a distinct “leader” phenotype with characteristic morphology and motility. However, the factors driving leader cell formation as well as the mechanisms regulating leader cell density durin...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Riahi, Reza, Sun, Jian, Wang, Shue, Long, Min, Zhang, Donna D., Wong, Pak Kin
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380165/
https://ncbi.nlm.nih.gov/pubmed/25766473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7556
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